ABSTRACT
Gastrointestinal stromal tumor (GIST) is the commonest mesenchymal tumor of gastrointestinal tract. Gastrointestinal bleeding, obstruction, pain and abdominal lump are the common clinical manifestations. Local or segmental resection provides satisfactory results. Aim: Our aim was to report our experience of gastrointestinal stromal tumors (GISTs) during the last 2 years. Methods: Between January 2017 and June 2019, we performed surgery for 12 cases of GIST. Metastases, recurrence and survival data were collected in relation to age, history, clinical presentation, location, size, resection margins and cellular features. Results: Resection was completed in 11 cases. In one case definitive surgery was abandoned due to local invasion and metastasis. Three patients with high risk GIST were treated with imatinib mesylate. Conclusion: Non-radical surgery in the form of local or segmental resection is the standard surgical approach for GIST management. Pathological and biological features of the neoplasm represent the most important factors predicting the prognosis.
ABSTRACT
Gastrointestinal stromal tumor (GIST) is the commonest mesenchymal tumor of gastrointestinal tract. Gastrointestinal bleeding, obstruction, pain and abdominal lump are the common clinical manifestations. Local or segmental resection provides satisfactory results. Aim: Our aim was to report our experience of gastrointestinal stromal tumors (GISTs) during the last 2 years. Methods: Between January 2017 and June 2019, we performed surgery for 12 cases of GIST. Metastases, recurrence and survival data were collected in relation to age, history, clinical presentation, location, size, resection margins and cellular features. Results: Resection was completed in 11 cases. In one case definitive surgery was abandoned due to local invasion and metastasis. Three patients with high risk GIST were treated with imatinib mesylate. Conclusion: Non-radical surgery in the form of local or segmental resection is the standard surgical approach for GIST management. Pathological and biological features of the neoplasm represent the most important factors predicting the prognosis.
ABSTRACT
Recently there has been an increase in the incidence of obstructive jaundice due to malignant causes. Our aim was to diagnose and compare the surgical procedures to palliative procedures. Methods: This study was conducted on 250 patients at S.C.B Medical College & hospital, Cuttack, Odisha. The diagnosis of mechanical obstruction to the biliary tree is often difficult as the clinical features and biochemical investigation results may vary. Results: Non operative management with endoscopic stenting and interventional radiological procedures (PTBD) was 1st choice in certain group of patients. Conclusion: Most common site of the tumors are in the head of the pancreas (56.8%). The maximum incidence of malignant obstructive jaundice is between age 51 years and 60 years (28.8%).